Which of the following was discovered by GN Ramachandran?

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SSC Selection Post 2024 (Graduate Level) Official Paper (Held On: 25 Jun, 2024 Shift 3)
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  1. Fluid mosaic model of a cell
  2. Plasma membrane
  3. Golgi bodies 
  4. Triple helical structure of collagen

Answer (Detailed Solution Below)

Option 4 : Triple helical structure of collagen
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English Language (Matric Level) Sectional Test - 01
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The correct answer is Triple helical structure of collagen.

Key Points

  • G.N. Ramachandran is renowned for his significant contributions to biochemistry, particularly for elucidating the triple helical structure of collagen.
  • His work established that collagen, a key structural protein in connective tissues, consists of three polypeptide chains that form a right-handed triple helix.
  • The discovery of collagen's structure has implications for medicine, particularly in understanding diseases related to connective tissues.
  • Ramachandran's work has earned him recognition as a pioneer in structural biology, influencing subsequent research in the field.

Additional Information

  • Fluid Mosaic Model of a Cell:
    • Proposed by Singer and Nicolson in 1972, this model describes the cell membrane as a dynamic and flexible structure with a mosaic of various proteins floating in or on the fluid lipid bilayer.
    • It highlights the importance of membrane proteins in functions such as signaling, transport, and maintaining cell shape.
  • Plasma Membrane:
    • The plasma membrane is the outer boundary of the cell that separates its interior from the external environment.
    • Composed of a lipid bilayer with embedded proteins, it regulates the movement of substances in and out of the cell, playing a crucial role in cell communication and homeostasis.
  • Golgi Bodies:
    • Also known as the Golgi apparatus, these organelles are involved in modifying, sorting, and packaging proteins and lipids for secretion or delivery to other organelles.
    • Discovered by Camillo Golgi in 1898, the Golgi apparatus is essential for processing molecules synthesized in the endoplasmic reticulum.
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